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Homeopathic Pharmacy |
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Preparation of Drugs & Homeopathic Scales of Dilution |
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Introduction - There are three essential processes involved in preparation of remedies: (a) Serial dilution, (b) Succussion, (c) Trituration. Dilution is the means by which we reduce the toxicity of the original crude drug. Serial dilution means that each dilution is prepared from the dilution that immediately preceded it. Succussion and trituration are the methods by which mechanical energy is delivered to our preparations in order to imprint the pharmacological message of the original drug upon the molecules of the diluent. From the pharmaceutical point of view there are two main classes of original substance: (a) Soluble, (b) Insoluble. In the class of soluble substance, mother tinctures (alcohol water extraction) of the plant material are used. The symbol ø is used to denote the mother tincture of any soluble substance. For soluble substance alcohol and water are applied. At each stage Rythmitical violent agitations are carried out, either by hand or machine, and this is known as "Succussion". Insoluble original (i.e. natural) substances are prepared in a different way. The diluent in one sense is Lactose. The physical process applied at each stage is known as 'Trituration'. It is a prolonged circular grinding with motar and pestle. Once this trituration has obtained 6x or 1/ 10 to the power of 6, it can be dispensed into alcohol or water diluent. Thereafter it is treated like a soluble substance. These two major scale of preparing medicine are denoted as 'c' for centsimal scale and 'x' for decimal scale. Centesimal scale involves a serial dilution 1/100, whereas decimal involves a serial trituration 1/10 : Potentisation of Drug - For the preparations of the homoeopathic potencies of liquid drug substances three scales are in use, i.e. (a) Decimal, (b) Centesimal and (c) Millesimal. For the preparations of potencies from solid drug substances: (a) Decimal and (b) Centesimal scales are in use. When trituration attains the 6x potency, then only it will be fit to be converted into liquid potency. |
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